COMPACT TUNABLE CR-LISAF LASER FOR INFRARED MATRIX-ASSISTED LASER DESORPTION IONIZATION/

Authors
SADEGHI M OLUMEE Z TANG XD VERTES A JIANG ZX HENDERSON AJ LEE HS PRASAD CR
Citation
M. Sadeghi et al., COMPACT TUNABLE CR-LISAF LASER FOR INFRARED MATRIX-ASSISTED LASER DESORPTION IONIZATION/, Rapid communications in mass spectrometry, 11(4), 1997, pp. 393-397
Citations number
12
Categorie Soggetti
Spectroscopy,"Chemistry Analytical
Journal title
Rapid communications in mass spectrometry → ACNP
ISSN journal
09514198
Volume
11
Issue
4
Year of publication
1997
Pages
393 - 397
Database
ISI
SICI code
0951-4198(1997)11:4<393:CTCLFI>2.0.ZU;2-A
Abstract
A tunable Cr:LiSAF laser-pumped optical parametric oscillator was used for mid-infrared matrix-assisted laser desorption/ionization (MALDI) mass spectrometry experiments. The mass spect a of substance P, bovine insulin and pd(T)(10) in the 2.88-2.96 pm range showed excellent sing le shot signal quality (signal-to-noise-ratio, resolution) but poor sh ot-to-shot reproducibility. The reproducibility is expected to improve with more stable laser design. No correlation was found between the a bsorption sepectrum of the matrix and the MALDI response. (C) 1997 by John Wiley & Sons, Ltd.