ETRETINATE MAY WORK WHERE ACITRETIN FAILS

Authors
BLEIKER TO BOURKE JF GRAHAMBROWN RAC HUTCHINSON PE
Citation
To. Bleiker et al., ETRETINATE MAY WORK WHERE ACITRETIN FAILS, British journal of dermatology, 136(3), 1997, pp. 368-370
Citations number
19
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
British journal of dermatology → ACNP
ISSN journal
00070963
Volume
136
Issue
3
Year of publication
1997
Pages
368 - 370
Database
ISI
SICI code
0007-0963(1997)136:3<368:EMWWAF>2.0.ZU;2-V
Abstract
Acitretin (Ro 10-1670, Neotigason), a second-generation monoaromatic r etinoid, is the main acid derivative and active metabolite of etretina te (Ro 10-9359, Tigason), Three patients who were unresponsive to trea tment with acitretin but who responded to etretinate are reported, Twe nty-nine patients in the U.K. are currently receiving etretinate on a named-patient basis. Possible explanations for the functional discrepa ncy between the two drugs are discussed.