CUTANEOUS INFECTION DUE TO CLADOPHIALOPHORA-BANTIANA IN A PATIENT RECEIVING IMMUNOSUPPRESSIVE THERAPY

Citation
Wk. Jacyk et al., CUTANEOUS INFECTION DUE TO CLADOPHIALOPHORA-BANTIANA IN A PATIENT RECEIVING IMMUNOSUPPRESSIVE THERAPY, British journal of dermatology, 136(3), 1997, pp. 428-430
Citations number
10
Categorie Soggetti
Dermatology & Venereal Diseases
ISSN journal
00070963
Volume
136
Issue
3
Year of publication
1997
Pages
428 - 430
Database
ISI
SICI code
0007-0963(1997)136:3<428:CIDTCI>2.0.ZU;2-#
Abstract
Cladophialophora bantiana (Xylohypha bantiana, Cladosporium trichoides ), a dematiaceous fungus, causes mainly infections of the central nerv ous system. Systemic antifungal therapy is apparently unsuccessful. Ex tracerebral involvement is uncommon and only few cases have been repor ted. We describe a 63-year-old patient, a kidney transplant recipient on prolonged prednisone and cyclosporin, who developed a large single lesion on the thigh from which Cladophialophora bantiana was cultured. A 3-month course of itraconazole 200 mg daily resulted in complete he aling of the lesion. To the best of our knowledge this is the first re port on cutaneous infection with Cladophialophora bantiana in an organ transplant recipient and the first in whom treatment with itraconazol e led to resolution.