KK MOUSE

Authors
Citation
H. Ikeda, KK MOUSE, Diabetes research and clinical practice, 24, 1994, pp. 190000313-190000316
Citations number
15
Categorie Soggetti
Gastroenterology & Hepatology","Endocrynology & Metabolism
ISSN journal
01688227
Volume
24
Year of publication
1994
Supplement
S
Pages
190000313 - 190000316
Database
ISI
SICI code
0168-8227(1994)24:<190000313:KM>2.0.ZU;2-6
Abstract
The KK mouse strain shows inherently glucose intolerance and insulin r esistance. When KK mice become obese by aging, dietary means or other ways, such a chemical diabetic state is changed to overt diabetic stat e associated with frank hyperglycemia and glucosuria. Therefore, the K K mouse is a good model for investigating a process of expression of o besity-associated diabetes.