DUPLICATION OF THE LANTIBIOTIC STRUCTURAL GENE IN M-TYPE-49 GROUP-A STREPTOCOCCUS STRAINS PRODUCING STREPTOCOCCIN-A-M49

Authors
HYNES WL FRIEND VL FERRETTI JJ
Citation
Wl. Hynes et al., DUPLICATION OF THE LANTIBIOTIC STRUCTURAL GENE IN M-TYPE-49 GROUP-A STREPTOCOCCUS STRAINS PRODUCING STREPTOCOCCIN-A-M49, Applied and environmental microbiology, 60(11), 1994, pp. 4207-4209
Citations number
15
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology
Journal title
Applied and environmental microbiology → ACNP
ISSN journal
00992240
Volume
60
Issue
11
Year of publication
1994
Pages
4207 - 4209
Database
ISI
SICI code
0099-2240(1994)60:11<4207:DOTLSG>2.0.ZU;2-W
Abstract
Streptococcin A-M49 is produced by certain strains of M-type 49 group A streptococci. The structural gene for streptococcin A-M49 was cloned after hybridization with a probe containing the scnA lantibiotic stru ctural gene. Sequence analysis revealed a duplication of the scnA gene ; each gene (scnA' and scnA'') encoded a 51-amino-acid prepeptide.