RISK-FACTORS AFFECTING THE MORTALITY IN ACUTE GASTRIC-MUCOSAL LESIONS

Forty-five patients with acute gastric mucosal lesions (AGML), operate d on in a 15-year period (1976-1990) were retrospectively analyzed to assess the factors affecting the mortality. The operative mortality ra te was 37.78%. Univariate and multivariate analysis were done to demon strate if any of the previously derived set of 15 clinical variables w as related to the operative mortality. The clinical variables used wer e age, sex, indication of initial hospitalization, hypotension, recent operation, NSAID use, AGML prophylaxis, transfusion, recent upper Gl bleeding, concurrent major medical illness, concurrent sepsis, type of operation, postoperative complication, rebleeding, and reoperation fo r AGML. Mean age, major medical illness, postoperative complication, r ebleeding, and reoperation were found to affect the prognosis accordin g to the univariate analysis. Only postoperative complication and conc urrent major medical illness were significant factors affecting the mo rtality when multivariate analysis was done. Further analysis showed t hat concurrent major medical illness and initial indication of hospita lization were the significant factors among the studied variables affe cting the postoperative complication rate. The type of operation did n ot alter the prognosis.