N. Nakamura et al., MUSCULAR-DYSTROPHY OF THE DIAPHRAGMATIC MUSCLES IN HOLSTEIN-FRIESIAN COWS, Journal of veterinary medical science, 56(5), 1994, pp. 993-994
Six Holstein-Friesian cows suffering from recurrent rumenal tympany we
re pathologically investigated. Macroscopical lesions associated with
the clinical symptoms were confined to the diaphragmatic muscles which
were pale, and stiff on palpation. Histopathological examination reve
aled various degenerative changes in diaphragmatic muscles as follows:
variation in muscle fiber diameter, vacuolar and hyalinized degenerat
ion of muscle fibers, fiber splitting, central core-like structures, s
arcoplasmic masses and ring fibers. These characteristic features in t
he present cases were consistent with dystrophy of the diaphragmatic m
uscles in Meuse-Rhine-Yssel cattle. From these observations, it is con
firmed that muscular dystrophy of the diaphragmatic muscles dose occur
in Holstein-Friesian cows, although a genetic mode was not proven.