8-AMINO-2'-DEOXYADENOSINE-2'-DEOXYTHYMIDINE BASE-PAIRING - IDENTIFICATION OF NOVEL REVERSE HOOGSTEEN MODE IN SOLUTION

Authors
KUMAR RK GUNJAL AD GANESH KN
Citation
Rk. Kumar et al., 8-AMINO-2'-DEOXYADENOSINE-2'-DEOXYTHYMIDINE BASE-PAIRING - IDENTIFICATION OF NOVEL REVERSE HOOGSTEEN MODE IN SOLUTION, Biochemical and biophysical research communications, 204(2), 1994, pp. 788-793
Citations number
16
Categorie Soggetti
Biology,Biophysics
Journal title
Biochemical and biophysical research communications → ACNP
ISSN journal
0006291X
Volume
204
Issue
2
Year of publication
1994
Pages
788 - 793
Database
ISI
SICI code
0006-291X(1994)204:2<788:8B-I>2.0.ZU;2-7
Abstract
A novel reversed Hoogsteen mode is observed for the base-pairing of 8- amino-2'-deoxyadenosine with 2'-deoxythymidine in low dielectric solve nt. The results may have important significance for designing novel DN A duplexes and triplexes incorporating 8-amino-dA. (C) 1994 Academic P ress, Inc.