Ttt. Kirchmann et al., CUTANEOUS ANGIOSARCOMA AS A 2ND MALIGNANCY IN A LYMPHEDEMATOUS LEG INA HODGKINS-DISEASE SURVIVOR, Journal of the American Academy of Dermatology, 31(5), 1994, pp. 861-866
Angiosarcoma is a rare and highly malignant neoplasm. Cutaneous angios
arcoma not associated with postmastectomy lymphedema is rare. There ar
e only eight reported cases of de velopment of cutaneous angiosarcoma
in a lymphedematous extremity in a patient with pre existing malignanc
y other than breast cancer. This is the first reported case of develop
ment of cutaneous angiosarcoma in a lymphedematous extremity in a Hodg
kin's disease survivor. A review of cutaneous angiosarcoma associated
with lymphedema and a discussion of the pathogenesis of angiosarcoma a
re included.