GROWTH-FACTORS IN ANGIOGENESIS

Several growth factors are potential inducers of neovascularization. T his property established from in vitro or in vivo studies suggest that these polypeptides might be involved in physiological angiogenesis. R ecent advances in the structure of the growth factors, identification of specific cell surface receptors and in their mechanisms of action b ring a better understanding of the biochemical events involved in angi ogenesis.