Ww. Tsai et al., POINT-OF-CARE VERSUS CENTRAL LABORATORY TESTING - AN ECONOMIC-ANALYSIS IN AN ACADEMIC-MEDICAL-CENTER, Clinical therapeutics, 16(5), 1994, pp. 898-910
A cost-effectiveness study was conducted to determine time and labor c
osts for point-of-care (POC) versus central laboratory testing. A pros
pective, observational time and motion study was carried out at a teac
hing hospital located in Philadelphia, Pennsylvania. The cohort consis
ted of 210 patients presenting to the emergency department who were tr
iaged at the urgent or emergent level during a 4-week period. Patients
who had blood drawn for a seven-chemistry profile (Chem-7), which inc
ludes analysis of sodium, potassium, chloride, carbon dioxide, blood u
rea nitrogen, glucose, and creatinine, or for cell blood count (CBC) t
ests as part of regular care, also had an additional split sample draw
n for POC analysis of sodium, potassium, chloride, blood urea nitrogen
, glucose, and/or hematocrit. Blood drawn for POC analysis did not req
uire additional needlestick(s), nor did it alter regular care procedur
es. Physicians and all emergency department staff participating in the
care of the patients were blinded to POC test results. Main outcome m
easures included test turnaround time (TAT), physician determination o
f impact of rapid TAT and laboratory values on therapeutic approach, a
nd cost per test for POC versus central laboratory testing. POC TAT wa
s a mean of 8 minutes (time from blood drawn to results shown on the P
OC device display). Central laboratory TAT was a mean of 59 minutes (t
ime from blood drawn to entry of results into mainframe computer). The
rapeutic TAT was a mean of 1 hour and 25 minutes (time from blood draw
n to analysis in central laboratory, to when the physician viewed test
results). After therapeutic course of care was decided for the patien
t, physicians reported that POC testing, independent of other rate-lim
iting steps, would have resulted in earlier therapeutic action for 40
of 210 (19.0%) patients. The cost per test for Chem-7 and CBC tests wa
s $11.14 and $9.48, respectively. The cost per test for POC analysis r
anged from $14.37 to $16.67, depending on the POC test volume (estimat
ed volume based on 20% to 50% of emergency department patients that ha
d either Chem-7 or CBC test done applied over the useful life of the P
OC testing equipment) and the personnel (nurse or emergency department
technician) who performed the test. With an increasing volume of POC
tests performed per unit time, costs for POC testing would be reduced
substantially. POC test costs are volume dependent under current reimb
ursement mechanisms for emergency department patient care services, fo
r example, free-for-service payment. Costs for POC tests versus compar
able central laboratory assays do not account for emergency department
throughput efficiency benefits, such as faster TAT and shortened leng
th of stay. From a clinical management perspective, patient consumer i
ssues such as expectations for timely and efficient health services de
livery and earlier physician decisions on course of care suggest that
selective use of POC testing in the emergency department can result in
long-standing cost savings to the hospital.