The spatial distribution of back scattering from a vertical cross-sect
ion of the nuclear area in non-cataractous human lens was investigated
. The cross-section was centred on the pupil. There is no significant
difference in average nuclear back scattering between sides. The distr
ibution of back scattering along an axis perpendicular to the anatomic
al axis can be modelled as a second-order polynomial, It is believed t
hat the increase of back scattering in the central region corresponds
to the peak protein concentration in the centre of the nucleus. This i
nformation was obtained by imaging back scattering with Scheimpflug ph
otography, The back scattering was measured photometrically in a 3 x 1
0 matrix of measuring areas within the lens nucleus. Each measuring ar
ea was 0.20 x 0.20 mm in size. It is anticipated that the established
model will allow detection of nuclear cataract with high sensitivity,
especially in early stages.