Over a period of 7 years 126 patients with rectosigmoid carcinoma cons
idered unsuitable for surgery underwent endoscopic Nd:YAG laser treatm
ent for palliation of symptoms and tumor eradication, if feasible. Alt
ogether 72 (59%) of the lesions had distal margins less than 7 cm from
the anus and 32 (23%) above the peritoneal reflection. In 14 patients
with tumor less than 3cm in diameter, symptomatic improvement was ach
ieved in all. Is the remaining 112 patients with larger tumors (81 gre
ater than 3/4 circumferential, mean length 5.5 cm) symptomatic improve
ment was achieved with repeated treatments (average 3.7) in 58 (71%).
All treatment failures occurred in patients with extensive tumors (17
initial, 12 Late). Rowel perforation did not occur and there was no tr
eatment related mortality. The average stay in hospital for all laser
patients was 9 days (32% of patients were outpatient attendance). Thes
e results suggest that laser therapy may be the palliative treatment o
f choice in patients with rectosigmoid carcinoma unsuitable for surger
y.