CENTRAL SEROTONERGIC HYPERRESPONSIVITY IN LATE-ONSET ALZHEIMERS-DISEASE

Authors
MCLOUGHLIN DM LUCEY JV DINAN TG
Citation
Dm. Mcloughlin et al., CENTRAL SEROTONERGIC HYPERRESPONSIVITY IN LATE-ONSET ALZHEIMERS-DISEASE, The American journal of psychiatry, 151(11), 1994, pp. 1701-1703
Citations number
15
Categorie Soggetti
Psychiatry,Psychiatry
Journal title
The American journal of psychiatry → ACNP
ISSN journal
0002953X
Volume
151
Issue
11
Year of publication
1994
Pages
1701 - 1703
Database
ISI
SICI code
0002-953X(1994)151:11<1701:CSHILA>2.0.ZU;2-E
Abstract
The prolactin response to oral d-fenfluramine (30 mg) was measured in nine patients with fate-onset Alzheimer's disease and in an elderly co mparison group. The serotonin-mediated prolactin response was signific antly greater in the patients with Alzheimer's disease than in the com parison group. This finding suggests that central serotonin responsivi ty is greater in Alzheimer's disease.