ASPECTS OF PLATELET STORAGE

Authors
Citation
Cf. Hogman, ASPECTS OF PLATELET STORAGE, Transfusion science, 15(4), 1994, pp. 351-355
Citations number
NO
Categorie Soggetti
Hematology
Journal title
ISSN journal
09553886
Volume
15
Issue
4
Year of publication
1994
Pages
351 - 355
Database
ISI
SICI code
0955-3886(1994)15:4<351:AOPS>2.0.ZU;2-X
Abstract
The proper storage of platelets requires sufficient knowledge of the b ehaviour of these cells, made by nature to react instantly. It is impo rtant not to activate them during preparation and storage and to maint ain oxidative metabolism at the highest possible degree. Optimally, th e citrate concentration in the storage medium should be 8-10 mmol/L. T he addition of acetate either to the anticoagulant or to a platelet ad ditive solution gives the potential for improved platelet storage. In order to evaluate the clinical efficiency of platelet concentrates (PC s), corrected count increment is to be recommended for frequent use. T he in vitro bleeding time seems to be a valuable supplement, both for research and clinical purposes. Bacterial contamination is a threat wh ich can be diminished by using an appropriate technique for preparatio n and storage. Rapid automated bacterial culture makes it possible to detect contamination which may be particularly important if the shelf life of PCs is being extended beyond the present 5 days.