The proper storage of platelets requires sufficient knowledge of the b
ehaviour of these cells, made by nature to react instantly. It is impo
rtant not to activate them during preparation and storage and to maint
ain oxidative metabolism at the highest possible degree. Optimally, th
e citrate concentration in the storage medium should be 8-10 mmol/L. T
he addition of acetate either to the anticoagulant or to a platelet ad
ditive solution gives the potential for improved platelet storage. In
order to evaluate the clinical efficiency of platelet concentrates (PC
s), corrected count increment is to be recommended for frequent use. T
he in vitro bleeding time seems to be a valuable supplement, both for
research and clinical purposes. Bacterial contamination is a threat wh
ich can be diminished by using an appropriate technique for preparatio
n and storage. Rapid automated bacterial culture makes it possible to
detect contamination which may be particularly important if the shelf
life of PCs is being extended beyond the present 5 days.