TECHNICAL AND CLINICAL-EXPERIENCE WITH PROTEIN-A IMMUNOADSORPTION COLUMNS

Authors
BELAK M BORBERG H JIMENEZ C OETTE K
Citation
M. Belak et al., TECHNICAL AND CLINICAL-EXPERIENCE WITH PROTEIN-A IMMUNOADSORPTION COLUMNS, Transfusion science, 15(4), 1994, pp. 419-422
Citations number
NO
Categorie Soggetti
Hematology
Journal title
Transfusion science → ACNP
ISSN journal
09553886
Volume
15
Issue
4
Year of publication
1994
Pages
419 - 422
Database
ISI
SICI code
0955-3886(1994)15:4<419:TACWPI>2.0.ZU;2-I
Abstract
Protein A adsorption (Immunosorba, Excorim, Sweden) is a potent tool f or the rapid removal of antibodies from the circulation. In comparison to conventional plasma exchange therapy, Protein A adsorption offers the advantage of processing large amounts of plasma, removing up to 87 % of the initial level of IgG in one session without a clinically sign ificant loss of fibrinogen. So far 61 treatments have been carried out in our department without serious side effects.