We. Charash et al., DELAYED SURGICAL FIXATION OF FEMUR FRACTURES IS A RISK FACTOR FOR PULMONARY FAILURE INDEPENDENT OF THORACIC TRAUMA, The journal of trauma, injury, infection, and critical care, 37(4), 1994, pp. 667-672
A recent retrospective analysis of femur fractures concluded that earl
y surgical fixation in patients who have sustained blunt thoracic trau
ma (AIS score for Thorax greater-than-or-equal-to 2) was a risk factor
for postoperative pulmonary failure. We conducted a review of all fem
ur fractures admitted to a level I trauma center from November, 1988 t
o May, 1993. Inclusion criteria were ISS greater-than-or-equal-to 18,
mid-shaft femur fractures treated with reamed intramedullary fixation,
and no mortalities secondary to head trauma or hemorrhagic shock. One
hundred thirty-eight patients met these criteria. Four patient groups
were created: N1-no thoracic trauma (AIS score for thorax < 2), and e
arly surgical fixation (<24 hours after injury, n = 49); N2-no thoraci
c trauma and delayed fixation (greater-than-or-equal-to24 hours, n = 8
); T1-thoracic trauma (AIS score for Thorax greater-than-or-equal-to 2
) and early fixation (n = 56); T2-thoracic trauma and delayed fixation
(n = 25). There were no significant differences in age, Injury Severi
ty Score, or Glasgow Coma Scale score between the four groups. Mortali
ty rate, length of stay (LOS), LOS in the TICU, and duration of mechan
ical ventilation tended to be greater in patients with delayed fractur
e fixation, however, this was not statistically significant. The N2 pa
tients had a pneumonia rate of 38% compared with 10% in group N1 (p =
0.07). The T2 patients had a pneumonia rate of 48% compared with 14% i
n group T1 (p = 0.002). The overall pulmonary complication rate (pneum
onia, adult respiratory distress syndrome, fat embolism syndrome, and
pulmonary embolus) was 56% in group T2 compared with 16% in group T1 (
p = 0.007). We conclude that delayed surgical fixation is associated w
ith a higher pulmonary complication rate, independent of blunt thoraci
c trauma.