MERKEL,FRIEDRICH,SIGMUND (1845-1919) AND HIS CELL

Citation
D. Kopera et K. Holubar, MERKEL,FRIEDRICH,SIGMUND (1845-1919) AND HIS CELL, EJD. European journal of dermatology, 4(7), 1994, pp. 506-508
Citations number
24
Categorie Soggetti
Dermatology & Venereal Diseases
ISSN journal
11671122
Volume
4
Issue
7
Year of publication
1994
Pages
506 - 508
Database
ISI
SICI code
1167-1122(1994)4:7<506:M(AHC>2.0.ZU;2-C
Abstract
Friedrich Sigmund Merkel was one of the leading anatomists and histopa thologists of the late 19th century. In search of direct junctions bet ween neurites and epidermal cells he dicovered the basic touch sensiti ve organ, describing it as ''touch cell'' in 1875. Several other scien tists were also engaged int he same field. One of them was Robert Bonn et, who eponymously named this cell after Merkel. The image of the Mer kel cell has been completed during the years. They have been identifie d as neuroendocrine cells, but still it remains undecided wether or no t the neuroendocrine tumor called ''Merkel cell carcinoma'' derives fr om Merkel cells.