CHIRALITY DIRECTED SELF-ASSEMBLY - RESOLUTION OF 2,5-DIAZABICYCLO[2.2.2]OCTANE-3,6-DIONE AND CRYSTAL-STRUCTURES OF ITS RACEMIC AND (-) ENANTIOMERIC FORMS

Authors
BRIENNE MJ GABARD J LECLERCQ M LEHN JM CESARIO M PASCARD C CHEVE M DUTRUCROSSET G
Citation
Mj. Brienne et al., CHIRALITY DIRECTED SELF-ASSEMBLY - RESOLUTION OF 2,5-DIAZABICYCLO[2.2.2]OCTANE-3,6-DIONE AND CRYSTAL-STRUCTURES OF ITS RACEMIC AND (-) ENANTIOMERIC FORMS, Tetrahedron letters, 35(44), 1994, pp. 8157-8160
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
44
Year of publication
1994
Pages
8157 - 8160
Database
ISI
SICI code
0040-4039(1994)35:44<8157:CDS-RO>2.0.ZU;2-O
Abstract
The chiral bicyclic bis-lactam 1 has been resolved and the crystal str uctures of the racemate (+/-)-1 and of enantiomerically pure (-)-1 hav e been determined. They show that the chiral nature of the substance d etermines the supramolecular architecture generated by hydrogen bondin g self-assembly, giving an infinite zig-zag chain for the racemate and a cyclic tetramer for the enantiomer.