A FACILE BIOMIMETIC SYNTHESIS OF UHLES KETONE BY THE REGIOSELECTIVE FRIEDEL-CRAFTS CYCLIZATION OF INDOLE-3-YLPROPIONYL CHLORIDE

Authors
TERANISHI K HAYASHI S NAKATSUKA S GOTO T
Citation
K. Teranishi et al., A FACILE BIOMIMETIC SYNTHESIS OF UHLES KETONE BY THE REGIOSELECTIVE FRIEDEL-CRAFTS CYCLIZATION OF INDOLE-3-YLPROPIONYL CHLORIDE, Tetrahedron letters, 35(44), 1994, pp. 8173-8176
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
44
Year of publication
1994
Pages
8173 - 8176
Database
ISI
SICI code
0040-4039(1994)35:44<8173:AFBSOU>2.0.ZU;2-7
Abstract
In the presence of a larg amount of oxocarbonium ion species generated from chloroacetyl chloride and aluminum chloride, 3-(1-trimtrhylacety lindol-3yl)-propionyl chloride reacts regioselectively to give a pival oyl derivative of Uhle's ketone in excellent yield