SPOROTRICHOID CUTANEOUS LEISHMANIASIS DUE TO LEISHMANIA-MAJOR OF DIFFERENT ZYMODEMES IN THE SUDAN AND SAUDI-ARABIA - A COMPARATIVE-STUDY

Sporotrichoid cutaneous leishmaniasis is due to dissemination of amast igotes via the lymphatics to the subcutaneous tissues. A comparison wa s made between the potential to disseminate by this route of 2 parasit es of different zymodemes in Sudan and Saudi Arabia. In Sudan cutaneou s leishmaniasis is caused by Leishmania major zymodeme LON-1, and in S audi Arabia by L. major LON-4. Sporotrichoid leishmaniasis was signifi cantly more common in Sudan, occurring in 23% of patients compared wit h 10% in Saudi Arabia. Lymph node involvement was slightly more preval ent in the Sudan. Clinical and pathological differences between subcut aneous nodules, particularly when they ulcerate, and multiple primary cutaneous lesions are described and treatment of localized and sporotr ichoid leishmaniasis is discussed. The pathological features of the pr imary lesions in the Sudan and Saudi Arabia were similar.