A. Kurjak et al., FETAL CHOROID-PLEXUS VASCULARIZATION ASSESSED BY COLOR-FLOW ULTRASONOGRAPHY, Journal of ultrasound in medicine, 13(11), 1994, pp. 841-844
Citations number
7
Categorie Soggetti
Acoustics,"Radiology,Nuclear Medicine & Medical Imaging
We investigated the development of intracranial vascularization in the
human fetus, with particular emphasis on the choroid plexus. The feta
l brain was visualized in 102 patients with healthy pregnancies betwee
n 9 and 16 weeks' gestation. Imaging was done transvaginally except in
the pregnancies of longer duration with unfavorable fetal positions.
Color flow imaging was used to identify vessels in the cranium and wit
hin the choroid plexus. Pulsed Doppler signals were obtained from an i
nternal carotid-middle cerebral artery and from a choroid plexus vesse
l. The pulsatility index was calculated from the Doppler spectral enve
lope. A major cerebral vessel could be seen at 9 weeks' gestation. Cho
roid plexus vessels were first seen at 10 weeks 3 days. Visualization
rates ranged from 35 to 75% for plexus vessels, and 65 to 100% for cer
ebral vessels. Visualization of choroid plexus vessels was maximal at
13 weeks. The pulsatility index for the cerebral arteries at this gest
ational period averaged 2.6 +/- 0.6. The result for the choroid plexus
was 1.66 +/- 0.5. (P < 0.001). Visualization of the vessels of the ch
oroid plexus increases and decreases as the gland develops and shrinks
. This developmental period also is the time of active neurogenesis.