Introduction: Surgical treatment for liver hydatid cyst has been consi
dered so far as standard therapy, but has a high recurrence rate as we
ll as morbidity and mortality. Case Report: We report a case of a 30-y
ear-old Saudi male who presented with obstructive jaundice, secondary
to a huge hydatid cyst of the liver of about 20 cm diameter. The cyst
was compressing the right lobe of the liver and biliary tree causing t
he obstructive jaundice. There was no evidence for rupture of the cyst
into the biliary tree; CT-guided percutaneous aspiration and drainage
of the cyst was performed successfully. This was followed by irrigati
on of the cyst with hypertonic saline via retained intracystic pigtail
catheters. Within the first 2 weeks the jaundice was resolved. Combin
ed medical therapy of albendazole and praziquantel was also administer
ed. The patient showed clear clinical improvement during regular follo
w-up. His repeated CT 4 months later showed disappearance of daughter
cysts. Conclusion: The case illustrates the possibility of avoiding su
rgical management and it illustrates the successful percutaneous manag
ement of such a large hydatid cyst causing obstructing jaundice.