CHEMISTRY OF TAXOIDS - ONE-STEP FUNCTIONALIZATION OF THE POSITION-1, POSITION-2, POSITION-9, POSITION-10 FROM THE SELECTIVELY PROTECTED 5-O-CINNAMOYLTAXICINE-I

Authors
ALMOURABIT A POUJOL H POUPAT C AHOND A POTIER P
Citation
A. Almourabit et al., CHEMISTRY OF TAXOIDS - ONE-STEP FUNCTIONALIZATION OF THE POSITION-1, POSITION-2, POSITION-9, POSITION-10 FROM THE SELECTIVELY PROTECTED 5-O-CINNAMOYLTAXICINE-I, Tetrahedron letters, 37(51), 1996, pp. 9189-9192
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
51
Year of publication
1996
Pages
9189 - 9192
Database
ISI
SICI code
0040-4039(1996)37:51<9189:COT-OF>2.0.ZU;2-6
Abstract
A simple one-step oxidative functionalization of the positions 1, 2, 9 and 10 of 5-O-cinnamoyltaxicine I is described. The benzylidene and e thylidene acetals were used as protective groups on the diols 1,2 and 9,10 respectively; their simultaneous direct conversion into 1-hydroxy -2-benzoyloxy and 9-keto-10-acetoxy derivative was achieved by CrO3/Ac OH or the Jones reagent Copyright (C) 1996 Published by Elsevier Scien ce Ltd