AB-INITIO CALCULATION OF VIBRATIONAL ABSORPTION AND CIRCULAR-DICHROISM SPECTRA USING DENSITY-FUNCTIONAL FORCE-FIELDS

The unpolarized absorption and circular dichroism spectra of the funda mental vibrational transitions of the chiral molecule 4-methyl-2-oxeta none are calculated ab initio. Harmonic force fields are obtained usin g density functional theory (DFT), MP2 and SCF methodologies, and a [5 s4p2d/3s2p] (TZ2P) basis set. DFT calculations use the LSDA, BLYP, and Becke3LYP (B3LYP) density functionals. Mid-IR spectra predicted using LSDA, BLYP, and B3LYP force fields are of significantly different qua lity, the B3LYP force field yielding spectra in clearly superior, and overall excellent, agreement with experiment. The MP2 force field yiel ds spectra in slightly worse agreement with experiment than the B3LYP force field. The SCF force field yields spectra in poor agreement with experiment. The basis set dependence of B3LYP force fields is also ex plored: the 6-31G and TZ2P basis sets give very similar results while the 3-21G basis set yields spectra in substantially worse agreement w ith experiment.