SYNTHESIS OF THE A E/F TRICYCLIC SECTION OF THE NORDITERPENOID ALKALOID METHYLLYCACONITINE, A POTENT INHIBITOR OF NEUROTRANSMISSION/

Authors
BAILLIE LC BEARDER JR WHITING DA
Citation
Lc. Baillie et al., SYNTHESIS OF THE A E/F TRICYCLIC SECTION OF THE NORDITERPENOID ALKALOID METHYLLYCACONITINE, A POTENT INHIBITOR OF NEUROTRANSMISSION/, Journal of the Chemical Society, Chemical Communications, (21), 1994, pp. 2487-2488
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
21
Year of publication
1994
Pages
2487 - 2488
Database
ISI
SICI code
0022-4936(1994):21<2487:SOTAET>2.0.ZU;2-Y
Abstract
The tricyclic amine (+/-)-2; R = H, with five stereogenic centres, rep resenting the A/E/F ring system of the norditerpene alkaloid methyllyc aconitine, is synthesised from penta-1,4-dien-3-ol in nine steps, with overall yield 16%.