EXPERT-SYSTEMS IN THE CONTROL OF ANIMAL-CELL CULTURE PROCESSES - POTENTIALS, FUNCTIONS, AND PERSPECTIVES

In recent years, the development of advanced systems for bioprocess mo nitoring and control has become an area of intensive research. Along w ith traditional techniques, there are several new approaches which are increasingly being applied to bioprocess operations. Among these, of special note is expert system technology, which provides possibilities for the design of efficient bioprocess control systems with new funct ional capabilities. This technology has been successfully applied to v ariety of microbial processes at laboratory and industrial scale. The present paper analyzes the possibility for application of expert syste ms to animal cell cultures processes whose high complexity is well sui ted to expert control. The discussion focuses on the organization and the functionality of the intelligent control systems, and covers some practical aspects of their design.