Squamous cell carcinoma of the esophagus is a tumor with poor prognosi
s; it is usually in an advanced state when first diagnosed. Because a
multimodal treatment approach is currently used, proper tumor staging
is essential to determine whether therapy should be directed toward cu
re or palliation. Important prognostic features of squamous cell carci
noma include the depth of tumor infiltration into or through the esoph
ageal wall and the presence of distant metastases. Imaging strategies
should not be limited to visualization of the tumor but also should be
directed toward accurate pretreatment staging. In this article, the a
uthors review the use of barium swallow, CT scans, and endoscopic ultr
asonography both alone and in combination to visualize and stage esoph
ageal carcinoma. The strengths and limitations of each modality are al
so discussed.