P. Wright et al., AN ASSOCIATION BETWEEN SPUTUM EOSINOPHILIA AND CARCINOMA OF THE LUNG - A STUDY OF 549 PATIENTS, Irish journal of medical science, 163(11), 1994, pp. 492-493
A prospective 11 year study of sputum cytology in 5,475 patients with
respiratory diseases other than asthma or Loeffler's syndrome showed t
hat carcinoma of the lung was the commonest single condition associate
d with a sputum eosinophilia: it occurred in 68 (12.4%) of the 549 pat
ients with pulmonary carcinoma. While clearly not a diagnostic finding
, sputum eosinophilia should stimulate, in appropriate cases, a furthe
r search for carcinoma. The cause or causes of the eosinophilia are no
t known at present but the body's reaction to malignancy is a topical
subject of study worldwide.