REACTIONS OF 16-NITROINDOLENINES OF THE VINCADIFFORMINE TYPE

Authors
LEWIN G ROLLAND Y SCHAEFFER C POISSON J
Citation
G. Lewin et al., REACTIONS OF 16-NITROINDOLENINES OF THE VINCADIFFORMINE TYPE, Heterocycles, 38(11), 1994, pp. 2401-2405
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
38
Issue
11
Year of publication
1994
Pages
2401 - 2405
Database
ISI
SICI code
0385-5414(1994)38:11<2401:RO1OTV>2.0.ZU;2-0
Abstract
The reactivity of 16-nitroindolenine (4), a byproduct of the aromatic nitration of vincadifformine (1), has been studied. In TFA 4 yielded 1 0-nitrovincadifformine (3) whereas acid hydrolytic treatment led to th e tetracyclic oxindole structure (8) by cleavage of the 2-16 bond. Red uction of 4 (SnCl2 or hydrogenolysis) allowed recovery of 1 in good yi eld.