PRESURGICAL, MULTIMODAL LOCALIZATION OF E PILEPTIC FOCI - FUNCTIONAL AND MORPHOLOGICAL TECHNIQUES INCLUDING INTENSIVE MONITORING MEG EEG AND IMAGING/

The most important preconditions for a successful epilepsy surgery pro gram are sufficient feasibilities for the localization of the epilepto genic brain tissue. In addition to the localization of the focal epile ptic activity the spatial correlation to functionally important brain regions has to be defined. The ''Erlangen Presurgical Epilepsy Program '' provides continuous day and night intensive EEG-video-monitoring, m easurement of interictal and ictal SPECt, brain metabolism, volumetric MRI and multichannel MEG. In this present contribution a special emph asis is given to methodological aspects of multichannel MEG-recordings and the results of this experimental technology.