The pyridazino[3,4-b]quinoxaline 12 was synthesized by the cyclization
of the alpha-arylhydrazonoacylhydrazide 11. The reaction of compound
12 with phosphoryl chloride gave pyridazino [3,4-b]quinoxaline 13, who
se reactions with sodium azide or cyclic secondary amines provided pyr
idazino[3,4-b]quinoxalines 14, 17 and 18, respectively. The acylhydraz
ide 15 was also cyclized to pyridazino[3,4-b]quinoxaline 16.