Lh. Larsson et al., 4-YEAR FOLLOW-UP AFTER UVULOPALATOPHARYNGOPLASTY IN 50 UNSELECTED PATIENTS WITH OBSTRUCTIVE SLEEP-APNEA-SYNDROME, The Laryngoscope, 104(11), 1994, pp. 1362-1368
Fifty unselected consecutive patients with obstructive sleep apnea syn
drome (OSAS) diagnosed by nocturnal recordings of respiration movement
s by a static charge sensitive bed (SCSB) and oximetry, alone or combi
ned with polysomnography, were studied. Renewed SCSB-oximetry recordin
gs evaluated treatment. Six months after surgery, 30 of 50 were classi
fied as responders. Twenty-one months after surgery, 19 of 49 were res
ponders. Patients who relapsed showed a significant increase in mean b
ody mass index (BMI). Four years after surgery, 24 of 48 patients were
responders. Preoperative BMI was significantly lower in the responder
group. Subsequent treatment was required in 15 nonresponders. There w
as no correlation between patients' subjective improvement and objecti
ve results. The study resulted in the following conclusions: 1. The re
sponder rate to UPPP in unselected patients is low 2. Obesity and high
indices of nocturnal respiratory disturbance are negative predictors.
3. The patients' subjective recovery alone must not be used for posto
perative evaluation. 4. With regular follow-up and the use of the trea
tment alternatives available today, the majority of OSAS patients can
receive effective treatment.