Dp. Kharadze et al., NEW BIODEGRADABLE POLYMERS DERIVED FROM [ N,N']-DIACYL-BISPHENYLALANINE, Vysokomolekularnye soedinenia. Seria A, 36(9), 1994, pp. 1462-1467
New polyamides and poly(amide-esters) derived from [N,N']-terephthaloy
l-bis-L-phenylalanine and [N,N']-adipoyl-bis-L-phenylalanine were synt
hesized using active polycondensation technique. The bis nucleophiles
used in the synthesis were hexamethylenediamine, methyl [N,N]-bistrime
thylsilyl-L-lysinate, and bis-L-phenylalanylbutane-1,4-diol di-p-tolue
nesulfonate. Some physicochemical properties and alpha-chymotrypsinoly
sis of the polymers prepared were studied. Factors affecting alpha-chy
motrypsinolysis of the polymer substrates were discussed.