A CASE OF PECULIAR PLANTAR WARTS - HUMAN PAPILLOMAVIRUS TYPE-60 INFECTION

Background: Various kinds of viral warts have their own typical clinic al appearances and histologic properties. From each of them, a corresp onding unique type of human papillomavirus (HPV) has been detected. Mo re than 60 types of HPV have been identified from the warts and other squamous cell epithelial tumors. Human papillomavirus type 60 has been identified in an epidermal cyst on the sole. We present a case of a p eculiar plantar wart infected with HPV type 60. Observations: A 21-yea r-old male student complained of yellowish hyperkeratotic slightly ele vated nodules on the right plantar arch. The surface of the nodules wa s not Papillary, but a normal ridge pattern of the sole could be trace d. Histologic findings included moderate acanthosis, papillomatosis, a nd eosinophilic intracytoplasmic large granules with or without surrou nded vacuoles. These were noted in the middle and upper epidermis, inc luding the hypertrophic stratum corneum. Virologic findings included H PV antigen detected by anti-HPV polyclonal anitibody. The DNA of HPV t ype 60 was detected by in situ hybridization. Conclusion: A new type o f plantar wart infected with HPV type 60 is reported. It shows unique clinical and histologic findings that can be distinguished from those of ordinary verruca or myrmecia on the sole.