PLASMA PYRIDOXAL-PHOSPHATE IN ANXIETY DISORDERS

One hundred and eighty-nine subjects with either generalized anxiety d isorder, panic disorder, or obsessive-compulsive disorder were evaluat ed for plasma pyridoxal phosphate (PLP) levels and compared with norma l controls, There was no difference in plasma PLP levels between the a nxiety disorder groups and normal controls. Low levels of plasma PLP w ere found in 42% of the controls. Our results suggest that previous re ports of low PLP levels in psychiatric patients are unlikely to be sig nificant in the etiology of the psychiatric disorders.