CT AND MRI OF GORHAM SYNDROME

Gorham syndrome, also known as massive osteolysis or vanishing bone, i s a rare disorder (135 cases reported) leading to extensive loss of bo ny matrix, replaced by proliferating thin-walled vascular channels. Th ree histologically proven cases of the disease are reported, including the clinical presentation and modern imaging features with CT (with 3 D reconstruction) as well as T1- and T2-weighted MRI. Two cases in you ng women were located in the pelvis with extensive osteolysis reaching to the acetabulum. The third case in a 2-month-old boy is the younges t case ever reported and involved the humerus. The radiological appear ance of the disease is discussed and the importance of the modern imag ing methods debated.