NITROXIDES - SYNTHESIS AND PARAMAGNETIC PROPERTIES OF AN ALPHA-HYDROXYMETHYL DERIVATIVE OF DOXYL

Authors
CHAOUNIBENABDALLAH A SUBRA G BONNET PA FERNANDEZ JP CHAPAT JP VALLET P MULLER RN
Citation
A. Chaounibenabdallah et al., NITROXIDES - SYNTHESIS AND PARAMAGNETIC PROPERTIES OF AN ALPHA-HYDROXYMETHYL DERIVATIVE OF DOXYL, Tetrahedron, 50(45), 1994, pp. 12923-12932
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
45
Year of publication
1994
Pages
12923 - 12932
Database
ISI
SICI code
0040-4020(1994)50:45<12923:N-SAPP>2.0.ZU;2-1
Abstract
The synthesis of new but unstable alpha-(hydroxymethyl)oxazolidin-3-ox yls was achieved after protection by silylation of the hydroxyl groups in order to avoid decomposition in diamagnetic nitrones. Relaxivity s tudies of 4-(hydroxymethyl)-2,2,4-trimethyloxazolidin-3-oxyl 1 show no beneficial effect due to the presence of an hydroxymethyl group in th e vicinity of the N-O group on the paramagnetic properties of nitroxid es.