A LOW-TEMPERATURE MITSUNOBU REACTION FOR THE INVERSION OF STERICALLY HINDERED SECONDARY ALCOHOLS

Authors
COLEMAN RS GRANT EB
Citation
Rs. Coleman et Eb. Grant, A LOW-TEMPERATURE MITSUNOBU REACTION FOR THE INVERSION OF STERICALLY HINDERED SECONDARY ALCOHOLS, Tetrahedron letters, 35(45), 1994, pp. 8341-8344
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
45
Year of publication
1994
Pages
8341 - 8344
Database
ISI
SICI code
0040-4039(1994)35:45<8341:ALMRFT>2.0.ZU;2-#
Abstract
Mitsunobu inversion of 1,1'-binaphthalenediol 3 with benzoic acid was studied, and the success of the reaction, was found to depend upon qua ntitative formation of bis-oxyphosphonium salt 6 at -23 degrees C, pri or to S(N)2 displacement at 25 degrees C.