CONSECUTIVE S(RN)1 AND E(RC)1 REACTIONS IN 5-NITROISOQUINOLINES

Authors
VANELLE P RATHELOT P MALDONADO J CROZET MP
Citation
P. Vanelle et al., CONSECUTIVE S(RN)1 AND E(RC)1 REACTIONS IN 5-NITROISOQUINOLINES, Tetrahedron letters, 35(45), 1994, pp. 8385-8388
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
45
Year of publication
1994
Pages
8385 - 8388
Database
ISI
SICI code
0040-4039(1994)35:45<8385:CSAERI>2.0.ZU;2-W
Abstract
The reaction of 1-(dichloromethyl)-5-nitroisoquinoline with 2-nitropro pane anion which gives 1-isopropylidenemethyl-5-nitroisoquinoline as m ajor product is shown to proceed by the consecutive S(RN)1 and E(RC)1 mechanisms. These mechanisms are confirmed by the inhibitory effects o f dioxygen, p-dinitrobenzene, cupric chloride and TEMPO.