MILD, EFFECTIVE AND SELECTIVE METHOD FOR THE SILYLATION OF ALCOHOLS USING SILAZANES PROMOTED BY CATALYTIC TETRABUTYLAMMONIUM FLUORIDE

Authors
TANABE Y MURAKAMI M KITAICHI K YOSHIDA Y
Citation
Y. Tanabe et al., MILD, EFFECTIVE AND SELECTIVE METHOD FOR THE SILYLATION OF ALCOHOLS USING SILAZANES PROMOTED BY CATALYTIC TETRABUTYLAMMONIUM FLUORIDE, Tetrahedron letters, 35(45), 1994, pp. 8409-8412
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
45
Year of publication
1994
Pages
8409 - 8412
Database
ISI
SICI code
0040-4039(1994)35:45<8409:MEASMF>2.0.ZU;2-I
Abstract
The presence of catalytic amounts (similar to 0.02 equiv.) of tetrabut ylamonnium fluoride (TBAF) significantly promoted the silylation of al cohols using a variety of available silazanes under mild conditions wi th high chemoselectivity, wherein the choice of silazanes allowed an a lternative method for the powerful silylation of various kinds of alco hols or the highly regioselective silylation of primary alcohols.