CRYPTOCOCCUS-NEOFORMANS INFECTION CAN ELICIT PROTECTIVE ANTIBODIES INMICE

Authors
MUKHERJEE J SCHARFF MD CASADEVALL A
Citation
J. Mukherjee et al., CRYPTOCOCCUS-NEOFORMANS INFECTION CAN ELICIT PROTECTIVE ANTIBODIES INMICE, Canadian journal of microbiology, 40(10), 1994, pp. 888-892
Citations number
39
Categorie Soggetti
Microbiology,Immunology,"Biothechnology & Applied Migrobiology",Biology
Journal title
Canadian journal of microbiology → ACNP
ISSN journal
00084166
Volume
40
Issue
10
Year of publication
1994
Pages
888 - 892
Database
ISI
SICI code
0008-4166(1994)40:10<888:CICEPA>2.0.ZU;2-K
Abstract
An IgG1 monoclonal antibody generated from a mouse infected with Crypt ococcus neoformans modified the course of intravenous cryptococcal inf ection in A/J mice by prolonging survival and reducing lung fungal bur den, brain mass, and serum polysaccharide levels. The results demonstr ate that C. neoformans infection can elicit useful antibodies.