HYPOTONIC MACULOPATHY AFTER TRABECULECTOMY WITH POSTOPERATIVE USE OF 5-FLUOROURACIL

We evaluated two patients who developed hypotonic maculopathy followin g trabeculectomy and adjunctive 5-fluorouracil injections. Both patien ts had ocular hypotony and decreased visual acuity following these inj ections. The first case showed marked choroidal foldings, retinal stri ae, increased retinal vascular tortuosity, engorgement and optic disc oedema. The second case had radial perifoveal retinal striae, increase d retinal vascular tortuosity and engorgement. The first patient regai ned pre-operative visual acuity while the second case had a visual acu ity of 20/25 without any intervention. Fundus changes were less marked 12 months after initial evaluation in both cases. Hypotonic maculopat hy is a reversible complication of trabeculectomies with adjunctive us e of 5-fluorouracil.