ELECTROSPRAY VS MATRIX-ASSISTED LASER-DESORPTION IONIZATION .1. SOME EXAMPLES IN THE PROTEIN FIELD

Authors
FAVRETTO D SERAGLIA R TRALDI P CURCURUTO O HAMDAN M
Citation
D. Favretto et al., ELECTROSPRAY VS MATRIX-ASSISTED LASER-DESORPTION IONIZATION .1. SOME EXAMPLES IN THE PROTEIN FIELD, Organic mass spectrometry, 29(10), 1994, pp. 526-532
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear",Spectroscopy
Journal title
Organic mass spectrometry → ACNP
ISSN journal
0030493X
Volume
29
Issue
10
Year of publication
1994
Pages
526 - 532
Database
ISI
SICI code
0030-493X(1994)29:10<526:EVMLI.>2.0.ZU;2-V
Abstract
Several proteins in the relative molecular mass (RMM) range 1150-29 00 0 are examined by means of both positive electrospray and matrix-assis ted laser desorption/ionization mass spectrometry. Accuracy of the mea sured RMMs, resolution and overall sensitivity are discussed. Tbe pres ence of more than one component in a number of the investigated compou nds permitted the assessment of both desorption methods for the analys is of mixtures. Solvent-induced conformational changes are linked to c harge-state distribution shifts observed in some positive electrospray mass spectre.