EWINGS-SARCOMA OF THE SKULL IN AN INFANT - A CASE-REPORT AND REVIEW

A 1-year-old female infant presented with a large 7-8 cm Ewing's sarco ma of the left parietal calvarium. It deeply indented the subjacent he misphere. Wide surgical excision was followed by chemotherapy but not radiation. The patient was clinically free of tumor when she expired 9 months later of sepsis. Though primary Ewing's sarcoma of the skull i s said to be relatively rare, we have tabulated 37 cases of this disor der, including the present one (we excluded mandibular tumors (>100 ca ses) since they are not usually treated by neurosurgeons). The mean ag e was ii years and of those available to follow-up, three quarters wer e tumor-free 6 months to 7 years postsurgery. The remainder survived a n average of 21 months. Ewing's tumors of the calvarium generally gran t a favorable prognosis following surgery and/or radiation and chemoth erapy. Those at the base of the brain may be more difficult to eradica te. In addition to primary Ewing's tumors, metastases to the skull and the blain from other primary sources in the skeleton have been docume nted in several reports.