This study examined whether severe emotional and physical trauma in th
e past affects the psychological condition of female patients currentl
y afflicted with cancer. Using the Brief Symptom Inventory (BSI), 41 w
omen with cancer, who had sustained extreme trauma during the Nazi Hol
ocaust of the midcentury, were compared with three different groups: a
matched group of cancer patients without Holocaust experience, a phys
ically healthy group of female Holocaust survivors, and healthy women
without a Holocaust past. Although psychological distress was comparab
le in the two healthy groups, it was far higher in Holocaust cancer pa
tients than in either their non-Holocaust counterparts or in the group
of healthy Holocaust survivors. These results may suggest that the se
vere trauma of the Holocaust could be responsible for markedly diminis
hed psychological response when such patients are confronted with new
stress.