Fewer than 1% of all lymphomas involve the esophagus; however, lymphom
a of the esophagus represents an important cause of dysphagia. This st
udy reviewed all cases of biopsy-proven lymphoma involving the esophag
us presenting at our institution between 1945 and 1999. Twenty-seven c
ases were identified. Three were primary esophageal lymphomas. Eleven
percent of the cases represented Hodgkin's disease. Eighty-nine percen
t were non-Hodgkin's lymphoma. Eighty-nine percent of the patients exp
erienced dysphagia. Eleven lymphomas (41%) were located at the gastroe
sophageal junction, while the other 17 were in the esophagus proper. S
even of these cases occurred at relapse. Three had mediastinal adenopa
thy with secondary esophageal involvement. Morbidity included tracheoe
sophageal fistula in 22%, and surgical repair was performed in half of
these cases. Vocal cord paralysis occurred in 22%, with minimal seque
lae. Esophageal stricture was present in 30%, usually necessitating di
lation. The presentation, diagnosis, and management of this problem ar
e multidisciplinary.