STEREOCHEMISTRY OF THE MICROBIAL REDUCTION OF KETOLACTONES

Authors
FRONZA G FUGANTI C PEDROCCHIFANTONI G PIERGIANNI V SARRA A SERVI S
Citation
G. Fronza et al., STEREOCHEMISTRY OF THE MICROBIAL REDUCTION OF KETOLACTONES, Biotechnology letters, 16(10), 1994, pp. 1047-1052
Citations number
6
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
16
Issue
10
Year of publication
1994
Pages
1047 - 1052
Database
ISI
SICI code
0141-5492(1994)16:10<1047:SOTMRO>2.0.ZU;2-0
Abstract
Keto-lactones 1-4 have been submitted to the action of a group of sele cted yeasts. The mode of reduction changes with the structure of the s ubstrate, yielding products with diastereo- and/or enantioselection. T he preparation of highly functionalised chiral intermediates in enanti omerically enriched form is envisaged.