EFFECTS OF POLAR ADDITIVES ON THE ENZYME ENANTIOSELECTIVITY OF AN ESTERIFICATION REACTION IN ORGANIC-SOLVENTS

Authors
DUAN G CHEN JY
Citation
G. Duan et Jy. Chen, EFFECTS OF POLAR ADDITIVES ON THE ENZYME ENANTIOSELECTIVITY OF AN ESTERIFICATION REACTION IN ORGANIC-SOLVENTS, Biotechnology letters, 16(10), 1994, pp. 1065-1068
Citations number
14
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
16
Issue
10
Year of publication
1994
Pages
1065 - 1068
Database
ISI
SICI code
0141-5492(1994)16:10<1065:EOPAOT>2.0.ZU;2-1
Abstract
The enantioselectivity of candida cylindracea lipase in esterification between ibuprofen and 1-butanol in organic solvents is influenced by adding a small amount of polar solvents. The results show that both th e solvents and the amount added affected the reaction. Addition of 0.0 5 % ( v/v) N,N-dimethylformamide increase the ee value of the ester fr om 57.5 % of no addition to that of 91 %