The Guillain-Barre syndrome, or acute inflammatory polyneuropathy, is
often regarded as a predominantly motor neuropathy with few sensory fe
atures, which has a good prognosis in most cases. However, pain is a c
ommon symptom occurring in up to 72% of cases. The types of pain are p
rotean including paraesthesiae, dysaesthesia, axial and radicular pain
, meningism, myalgia, joint pain and visceral discomfort, etc., and pa
tients may present in a variety of clinical settings such as intensive
care units, acute medical wards or rehabilitation departments. These
factors, combined with the fact that the condition is relatively uncom
mon, means that no controlled trial of pain management has been done a
nd a range of treatments has been proposed. We review the various pain
s which may be associated with Guillain-Barre syndrome and discuss sug
gestions for their management.